T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody (Biotin)
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody (Biotin)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx105963
Tested Applications
ELISA
Description
T-cell surface glycoprotein CD3 epsilon chain Antibody (Biotin) is a Rabbit Polyclonal antibody against T-cell surface glycoprotein CD3 epsilon chain conjugated to Biotin.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Immunogen: Recombinant human T-cell surface glycoprotein CD3 epsilon chain protein (23-207AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P07766 |
| Gene ID | 916 |
| OMIM | 186830 |
| Alias | T3E,TCRE,IMD18,CD3epsilon,T-cell surface glycoprotein CD3 epsilon chain,T-cell surface antigen T3/Leu-4 epsilon chain |
| Background | Antibody anti-CD3E |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD3E (CD3 epsilon) is one of the key subunits of the T-cell receptor (TCR)-CD3 complex, which is vital for T-cell activation and immune responses. The TCR complex allows T lymphocytes to recognize and respond to antigens presented by major histocompatibility complex (MHC) molecules on antigen-presenting cells (APCs). CD3E plays a critical role in assembling the TCR-CD3 complex and facilitating signal transduction after antigen recognition. The CD3E gene is located on chromosome 11q23 and encodes the CD3ε chain, a type I transmembrane protein essential for the assembly, expression, and signaling function of the TCR. Along with other CD3 subunits (CD3δ, CD3γ, and CD3ζ), CD3E forms part of the signal-transducing complex that transmits signals from the TCR upon antigen engagement. This signal initiates the cascade that leads to T-cell activation, differentiation, and proliferation, all of which are crucial for immune defense against pathogens.
Productos relacionados
T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody
CD3E Antibody is a Rabbit Polyclonal antibody against CD3E. The protein encoded by this gene is the CD3-epsilon polypept…
Ver producto
T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody
CD3 is a component of T cell surface receptor (TCR), it cantains 5 invariable chains: gamma, delta, epsilon-, and zeta/e…
Ver producto
T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3 gamma, delta and - zeta, and th…
Ver producto