T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody (APC / Cyanine 7)
338€ (0.1 mg)
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935106861
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name
T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody (APC / Cyanine 7)
category
Primary Antibodies
provider
Abbexa
reference
abx140989
tested applications
FCM
Description
T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody (APC / Cyanine 7) is a Hamster Monoclonal against T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) |
| Host | Hamster |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Conjugation | APC / Cyanine 7 |
| Isotype | IgG Kappa |
| Clone ID | T739 |
| Size 1 | 0.1 mg |
| Tested Applications | FCM |
| Buffer | PBS solution with 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P22646 |
| Gene ID | 12501 |
| Alias | T3E,TCRE,IMD18,CD3epsilon,T-cell surface glycoprotein CD3 epsilon chain,T-cell surface antigen T3/Leu-4 epsilon chain |
| Background | Antibody anti-CD3E |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
CD3E (CD3 epsilon) is one of the key subunits of the T-cell receptor (TCR)-CD3 complex, which is vital for T-cell activation and immune responses. The TCR complex allows T lymphocytes to recognize and respond to antigens presented by major histocompatibility complex (MHC) molecules on antigen-presenting cells (APCs). CD3E plays a critical role in assembling the TCR-CD3 complex and facilitating signal transduction after antigen recognition. The CD3E gene is located on chromosome 11q23 and encodes the CD3ε chain, a type I transmembrane protein essential for the assembly, expression, and signaling function of the TCR. Along with other CD3 subunits (CD3δ, CD3γ, and CD3ζ), CD3E forms part of the signal-transducing complex that transmits signals from the TCR upon antigen engagement. This signal initiates the cascade that leads to T-cell activation, differentiation, and proliferation, all of which are crucial for immune defense against pathogens.
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