T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody (APC / Cyanine 7)

Este producto es parte de CD3E - CD3 epsilon subunit of T-cell receptor complex
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468€ (100 tests)

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935106861
info@markelab.com
name
T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody (APC / Cyanine 7)
category
Primary Antibodies
provider
Abbexa
reference
abx140984
tested applications
FCM

Description

T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody (APC / Cyanine 7) is a Mouse  against T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E)
Host
Mouse
Reactivity
Human, Monkey
Conjugation
APC / Cyanine 7
Isotype
IgG1
Clone ID
F864
Size 1
100 tests
Tested Applications
FCM
Buffer
Stabilizing PBS solution containing 15 mM sodium azide.
Availability
Shipped within 5-12 working days.
Storage
Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze.
Dry Ice
No
UniProt ID
P07766
Gene ID
916
Alias
T3E,TCRE,IMD18,CD3epsilon,T-cell surface glycoprotein CD3 epsilon chain,T-cell surface antigen T3/Leu-4 epsilon chain
Background
Antibody anti-CD3E
Status
RUO

Descripción

CD3E (CD3 epsilon) is one of the key subunits of the T-cell receptor (TCR)-CD3 complex, which is vital for T-cell activation and immune responses. The TCR complex allows T lymphocytes to recognize and respond to antigens presented by major histocompatibility complex (MHC) molecules on antigen-presenting cells (APCs). CD3E plays a critical role in assembling the TCR-CD3 complex and facilitating signal transduction after antigen recognition. The CD3E gene is located on chromosome 11q23 and encodes the CD3ε chain, a type I transmembrane protein essential for the assembly, expression, and signaling function of the TCR. Along with other CD3 subunits (CD3δ, CD3γ, and CD3ζ), CD3E forms part of the signal-transducing complex that transmits signals from the TCR upon antigen engagement. This signal initiates the cascade that leads to T-cell activation, differentiation, and proliferation, all of which are crucial for immune defense against pathogens.

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