T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody (APC)

Este producto es parte de CD3E - CD3 epsilon subunit of T-cell receptor complex
Product Graph
689€ (100 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody (APC)
category
Primary Antibodies
provider
Abbexa
reference
abx270544
tested applications
FCM

Description

T-Cell Surface Glycoprotein CD3 Epsilon (CD3e) Antibody (APC) is a Rabbit Polyclonal Antibody conjugated to APC against T-Cell Surface Glycoprotein CD3 Epsilon (CD3e) for use in flow cytometry.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E)
Host
Rabbit
Reactivity
Mouse
Recommended Dilution
FCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
APC
Isotype
IgG
Purification
Purified by antigen-specific affinity chromatography.
Size 1
100 tests
Size 2
200 tests
Size 3
500 tests
Form
Liquid
Tested Applications
FCM
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light.
Dry Ice
No
Alias
T3E,TCRE,IMD18,CD3epsilon,T-cell surface glycoprotein CD3 epsilon chain,T-cell surface antigen T3/Leu-4 epsilon chain
Background
Antibody anti-CD3E
Status
RUO

Descripción

CD3E (CD3 epsilon) is one of the key subunits of the T-cell receptor (TCR)-CD3 complex, which is vital for T-cell activation and immune responses. The TCR complex allows T lymphocytes to recognize and respond to antigens presented by major histocompatibility complex (MHC) molecules on antigen-presenting cells (APCs). CD3E plays a critical role in assembling the TCR-CD3 complex and facilitating signal transduction after antigen recognition. The CD3E gene is located on chromosome 11q23 and encodes the CD3ε chain, a type I transmembrane protein essential for the assembly, expression, and signaling function of the TCR. Along with other CD3 subunits (CD3δ, CD3γ, and CD3ζ), CD3E forms part of the signal-transducing complex that transmits signals from the TCR upon antigen engagement. This signal initiates the cascade that leads to T-cell activation, differentiation, and proliferation, all of which are crucial for immune defense against pathogens.

Related Products

APC-30002

APC Anti-Mouse CD3E (145-2C11)

Ver Producto
EH1976

Human CD3E (T-cell surface glycoprotein CD3 epsilon chain) ELISA Kit

Ver Producto
F488-30002

FineTest®488 Anti-Mouse CD3E (145-2C11)

Ver Producto