T-Cell Surface Glycoprotein Cd1E, Membrane-Associated (CD1E) Antibody (Biotin)
169€ (20 µg)
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Name
T-Cell Surface Glycoprotein Cd1E, Membrane-Associated (CD1E) Antibody (Biotin)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx337912
Tested Applications
ELISA
Description
CD1E Antibody (Biotin) is a Rabbit Polyclonal against CD1E.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: T-Cell Surface Glycoprotein Cd1E, Membrane-Associated (CD1E) Immunogen: Recombinant Human T-cell surface glycoprotein CD1e, membrane-associated protein (198-294AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P15812 |
| Gene ID | 913 |
| Alias | R2,CD1A,T-cell surface glycoprotein CD1e membrane-associated,hCD1e,R2G1 |
| Background | Antibody anti-CD1E |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD1E molecule is a member of the CD1 family of glycoproteins, which are antigen-presenting molecules structurally related to the major histocompatibility complex (MHC) class I proteins. CD1 proteins are unique in their ability to present lipid and glycolipid antigens rather than peptide antigens, which are typically presented by MHC molecules. CD1E plays a specialized role within the CD1 family, particularly in the intracellular processing and presentation of lipid antigens, distinguishing it from other CD1 molecules that are predominantly involved in antigen presentation at the cell surface. CD1E is critical for the proper functioning of lipid antigen presentation, especially in professional antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. While other CD1 family members (e.g., CD1A, CD1B, CD1C, and CD1D) directly present lipid antigens to T cells, CD1E’s primary function is to facilitate the processing of complex lipids into smaller components that can be presented by other CD1 molecules. This intracellular processing is essential for generating the lipid antigens that eventually engage T cells, such as natural killer T (NKT) cells or conventional T cells, in the immune response to pathogens like mycobacteria, fungi, and certain viruses.
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