T-cell Surface Glycoprotein CD1b (CD1B) Antibody
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Description
CD1B Antibody is a Rabbit Polyclonal against CD1B.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | T-cell Surface Glycoprotein CD1b (CD1B) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P29016 |
| Gene ID | 910 |
| NCBI Accession | NP_001755.1, NM_001764.2 |
| OMIM | 188360 |
| Alias | R1,CD1,CD1A,T-cell surface glycoprotein CD1b |
| Background | Antibody anti-CD1B |
| Status | RUO |
Descripción
CD1B is a transmembrane glycoprotein that belongs to the CD1 family, which is structurally related to major histocompatibility complex (MHC) class I molecules. Encoded by the CD1B gene, it is primarily involved in the presentation of lipid and glycolipid antigens to T-cells, particularly a subset of T-cells known as invariant natural killer T-cells (iNKT). CD1B molecules are critical for immune responses to mycobacterial and other pathogen-derived lipids. Unlike MHC molecules, CD1B specializes in presenting lipid-based antigens rather than peptide antigens. It is expressed on antigen-presenting cells (APCs) such as dendritic cells, monocytes, and certain thymocytes.
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