T-Cell-Specific Surface Glycoprotein CD28 (CD28) Antibody (PE)
520€ (100 tests)
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935106861
info@markelab.com
name
T-Cell-Specific Surface Glycoprotein CD28 (CD28) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx415422
tested applications
FCM
Description
Cluster of Differentiation 28 (CD28) Antibody (PE) is a Rat Monoclonal antibody against Cluster of Differentiation 28 (CD28).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | T-Cell-Specific Surface Glycoprotein CD28 (CD28) |
| Host | Rat |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG2b |
| Purification | Purified |
| Size 1 | 100 tests |
| Form | Lyophilized |
| Tested Applications | FCM |
| Buffer | PBS, 1% BSA. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Store at -20 °C or -80 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P10747 |
| Alias | Tp44,T-cell-specific surface glycoprotein CD28 |
| Background | Antibody anti-CD28 |
| Status | RUO |
Descripción
CD28 is a pivotal co-stimulatory molecule expressed on the surface of T cells. It plays a crucial role in the activation and survival of T cells, which are essential components of the adaptive immune system. CD28 is predominantly found on CD4+ T helper cells, although it is also present on a subset of CD8+ cytotoxic T cells. The interaction of CD28 with its ligands, CD80 (B7-1) and CD86 (B7-2), on antigen-presenting cells (APCs) provides the necessary secondary signals that, together with signals from the T cell receptor (TCR), lead to full T cell activation, proliferation, and differentiation. The presence and function of CD28 are vital for initiating effective immune responses and for maintaining T cell homeostasis and tolerance.
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