T-Cell-Specific Surface Glycoprotein CD28 (CD28) Antibody (APC / Cyanine 7)

Este producto es parte de CD28 molecule
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468€ (100 tests)

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935106861
info@markelab.com
name
T-Cell-Specific Surface Glycoprotein CD28 (CD28) Antibody (APC / Cyanine 7)
category
Primary Antibodies
provider
Abbexa
reference
abx140933
tested applications
FCM

Description

T-Cell-Specific Surface Glycoprotein CD28 (CD28) Antibody (APC / Cyanine 7) is a Mouse Monoclonal against T-Cell-Specific Surface Glycoprotein CD28 (CD28).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetT-Cell-Specific Surface Glycoprotein CD28 (CD28)
HostMouse
ReactivityHuman, Monkey
ClonalityMonoclonal
ConjugationAPC / Cyanine 7
IsotypeIgG1 Kappa
Clone IDK486
Size 1100 tests
Tested ApplicationsFCM
BufferStabilizing PBS solution containing 15 mM sodium azide.
AvailabilityShipped within 5-12 working days.
StorageStore in the dark at 2-8°C. Avoid exposure to light. Do not freeze.
Dry IceNo
UniProt IDP10747
Gene ID940
AliasTp44,T-cell-specific surface glycoprotein CD28
BackgroundAntibody anti-CD28
StatusRUO

Descripción

CD28 is a pivotal co-stimulatory molecule expressed on the surface of T cells. It plays a crucial role in the activation and survival of T cells, which are essential components of the adaptive immune system. CD28 is predominantly found on CD4+ T helper cells, although it is also present on a subset of CD8+ cytotoxic T cells. The interaction of CD28 with its ligands, CD80 (B7-1) and CD86 (B7-2), on antigen-presenting cells (APCs) provides the necessary secondary signals that, together with signals from the T cell receptor (TCR), lead to full T cell activation, proliferation, and differentiation. The presence and function of CD28 are vital for initiating effective immune responses and for maintaining T cell homeostasis and tolerance.
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