T-Cell-Specific Surface Glycoprotein CD28 (CD28) Antibody (APC)

104€ (50 tests)
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935106861
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name
T-Cell-Specific Surface Glycoprotein CD28 (CD28) Antibody (APC)
category
Primary Antibodies
provider
Abbexa
reference
abx228279
tested applications
FCM
Description
CD28 Antibody (APC) is a Mouse Monoclonal Antibody against CD28.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | T-Cell-Specific Surface Glycoprotein CD28 (CD28) |
Host | Hamster |
Reactivity | Mouse |
Clonality | Monoclonal |
Conjugation | APC |
Isotype | IgG |
Size 1 | 50 tests |
Size 2 | 100 tests |
Size 3 | 200 tests |
Tested Applications | FCM |
Buffer | PBS with 0.05% Proclin300, 1% BSA. |
Availability | Shipped within 5-15 working days. |
Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze. |
Dry Ice | No |
UniProt ID | P31041 |
Gene ID | 12487 |
Alias | Tp44,T-cell-specific surface glycoprotein CD28 |
Background | Antibody anti-CD28 |
Status | RUO |
Descripción
CD28 is a pivotal co-stimulatory molecule expressed on the surface of T cells. It plays a crucial role in the activation and survival of T cells, which are essential components of the adaptive immune system. CD28 is predominantly found on CD4+ T helper cells, although it is also present on a subset of CD8+ cytotoxic T cells. The interaction of CD28 with its ligands, CD80 (B7-1) and CD86 (B7-2), on antigen-presenting cells (APCs) provides the necessary secondary signals that, together with signals from the T cell receptor (TCR), lead to full T cell activation, proliferation, and differentiation. The presence and function of CD28 are vital for initiating effective immune responses and for maintaining T cell homeostasis and tolerance.
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