T-Cell-Specific Surface Glycoprotein CD28 (CD28) Antibody

Este producto es parte de CD28 molecule
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299€ (0.1 mg)

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935106861
info@markelab.com
name
T-Cell-Specific Surface Glycoprotein CD28 (CD28) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx139215
tested applications
WB, IHC, IF/ICC, FCM, IP, FUNC

Description

CD28 Antibody is a Mouse Monoclonal against CD28.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
T-Cell-Specific Surface Glycoprotein CD28 (CD28)
Host
Mouse
Reactivity
Human, Monkey
Recommended Dilution
Validated in IHC-F and ICC. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1 Kappa
Clone ID
K486
Purity
> 95% (SDS-PAGE)
Purification
Purified by Protein A affinity chromatography.
Size 1
0.1 mg
Tested Applications
WB, IHC, IF/ICC, FCM, IP, FUNC
Buffer
LE/AF PBS solution, 0.2 µm filter sterilized.
Availability
Shipped within 5-12 working days.
Storage
Store at 2-8°C. Do not freeze.
Dry Ice
No
UniProt ID
P10747
Gene ID
940
Alias
Tp44,T-cell-specific surface glycoprotein CD28
Background
Antibody anti-CD28
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

CD28 is a pivotal co-stimulatory molecule expressed on the surface of T cells. It plays a crucial role in the activation and survival of T cells, which are essential components of the adaptive immune system. CD28 is predominantly found on CD4+ T helper cells, although it is also present on a subset of CD8+ cytotoxic T cells. The interaction of CD28 with its ligands, CD80 (B7-1) and CD86 (B7-2), on antigen-presenting cells (APCs) provides the necessary secondary signals that, together with signals from the T cell receptor (TCR), lead to full T cell activation, proliferation, and differentiation. The presence and function of CD28 are vital for initiating effective immune responses and for maintaining T cell homeostasis and tolerance.

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