Syntrophin, alpha 1 Protein

Este producto es parte de SNTA1 - Alpha-1-syntrophin
Product Graph
234€ (2 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Syntrophin, alpha 1 Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262487
tested applications
SDS-PAGE

Description

SNTA1 is a recombinant protein.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
SNTA1
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 80% (SDS-PAGE)
Size 1
2 µg
Size 2
10 µg
Size 3
1 mg
Form
Liquid 
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Dry Ice
No
UniProt ID
Q13424
Alias
SNTA1, LQT12, SNT1, TACIP1, dJ1187J4.5, Syntrophin, alpha 1, syntrophin alpha 1
Background
Protein SNTA1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Alpha-1-syntrophin (SNTA1) is a modular adaptor protein that interacts with members of the dystrophin-associated glycoprotein complex (DGC), linking the cytoskeleton to membrane-bound signaling proteins. It contains PDZ, PH, and syntrophin-specific domains that facilitate interactions with signaling molecules such as ion channels, nitric oxide synthase (NOS), and kinases, enabling the coordination of signal transduction pathways involved in membrane stability, ion homeostasis, and cellular signaling. SNTA1 is widely expressed in skeletal and cardiac muscle, where it regulates membrane integrity, ion transport, and nitric oxide signaling, critical for muscle contraction and vascular function. Dysregulation of SNTA1 is linked to muscular dystrophies, cardiac arrhythmias, and cancers due to its role in maintaining cytoskeletal organization and signaling balance. Mutations in SNTA1 are associated with long QT syndrome, a condition characterized by cardiac arrhythmias and impaired ion channel regulation. Functional studies highlight its essential role in maintaining cellular signaling, membrane structure, and tissue homeostasis under physiological and pathological conditions.

Related Products

P5732

Recombinant Human SNTA1

Ver Producto
abx137461

Alpha-1-syntrophin (SNTA1) Antibody

Alpha-1-syntrophin (SNTA1) Antibody is a Mouse Monoclonal antibody against Alpha-1-syntrophin (SNTA1).

Ver Producto
abx211869

Alpha-1-syntrophin (SNTA1) Antibody

SNTA1 Antibody is a Rabbit Polyclonal against SNTA1.

Ver Producto