Syk (pT525 / 526) Antibody
292.5€ (50 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Syk (pT525 / 526) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx031923
Tested Applications
ELISA, WB, IHC
Description
Syk is a positive effector of BCR-stimulated responses. This protein couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Syk (pT525/526) Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y525/526 of human Syk. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/250, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 72.1 kDa |
| Purification | Purified by protein G affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Size 1 | 50 µl |
| Size 2 | 200 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P43405 |
| NCBI Accession | NP_001128524.1, NP_001167638.1, NP_001167639.1, NP_003168.2 |
| Background | Antibody anti-Syk |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Productos relacionados
Mouse Syk Antibody
Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium …
Ver producto Syk (pT525 / 526) Antibody
Syk is a positive effector of BCR-stimulated responses. This protein couples the B-cell antigen receptor (BCR) to the mo…
Ver producto
Spleen Associated Tyrosine Kinase Phospho-Tyr323 (SYK pY323) Antibody
SYK (pY323) Antibody is a Rabbit Polyclonal antibody against SYK (pY323).…
Ver producto