Suppressor of IKBKE 1 (Sike1) Antibody

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292.5€ (80 µl)

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935106861
info@markelab.com
name
Suppressor of IKBKE 1 (Sike1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx031456
tested applications
ELISA, WB

Description

Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Suppressor of IKBKE 1 (Sike1)
Immunogen: KLH-conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1.
Host
Rabbit
Reactivity
Mouse
Recommended Dilution
WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 23.5 kDa
Purification
Purified through a protein A column, followed by peptide affinity purification.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9CPR7
Background
Antibody anti-Sike1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

Related Products

abx031456

Suppressor of IKBKE 1 (Sike1) Antibody

Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).

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