Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1) Antibody

Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1) Antibody
292.5€ (80 µl)

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Name
Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx033739
Tested Applications
ELISA, WB, IF/ICC

Description

CYP17A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17, 20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in CYP17A1 gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17, 20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

Documentos del producto

Instrucciones
Data sheet
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Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1)
Immunogen: KLH-conjugated synthetic peptide between 358-388 amino acids from the Central region of human CYP17A1.
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 57.4 kDa
Purification
Purified Rabbit Polyclonal Antibody.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB, IF/ICC
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P05093
NCBI Accession
NP_000093.1
Background
Antibody anti-CYP17A1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

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