Thialysine N-Epsilon-Acetyltransferase (SAT2) Antibody
377€ (100 µg)
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Name
Thialysine N-Epsilon-Acetyltransferase (SAT2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx237614
Tested Applications
ELISA, WB, IHC
Description
SAT2 Antibody is a Rabbit Polyclonal against SAT2.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Thialysine N-Epsilon-Acetyltransferase (SAT2) Immunogen: spermidine/spermine N1-acetyltransferase family member 2 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 19 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96F10 |
| Gene ID | 112483 |
| OMIM | 611463 |
| Alias | SSAT-2,SSAT2,Thialysine N-epsilon-acetyltransferase,Diamine acetyltransferase 2 |
| Background | Antibody anti-SAT2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Spermidine/Spermine N1 Acetyltransferase 2 (SAT2) is a lesser-studied acetyltransferase enzyme that shares functional similarities with SAT1 in catalyzing the acetylation of polyamines like spermidine and spermine Although SAT2 has a lower expression profile compared to SAT1, it participates in regulating intracellular polyamine levels and influences their transport and breakdown Emerging evidence suggests SAT2 is involved in cellular responses to stress and apoptosis, particularly under conditions where polyamine metabolism is disrupted Dysregulation of SAT2 expression may contribute to cancer progression, as polyamine catabolism is critical for controlling cell proliferation, survival, and metabolic adaptation Studies also indicate that SAT2 plays a role in modulating oxidative stress and mitochondrial function, linking its activity to cellular homeostasis and stress responses While its precise physiological roles are still being defined, SAT2’s involvement in polyamine metabolism underscores its importance in maintaining cellular growth and metabolic balance
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