Thialysine N-Epsilon-Acetyltransferase (SAT2) Antibody

Este producto es parte de SAT - Spermidine/Spermine N1-Acetyltransferase
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357.5€ (100 µg)

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935106861
info@markelab.com
name
Thialysine N-Epsilon-Acetyltransferase (SAT2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx122906
tested applications
ELISA, WB, IHC

Description

Rabbit Polyclonal against the SAT2 protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Thialysine N-Epsilon-Acetyltransferase (SAT2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by antigen affinity column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB, IHC
Buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q96F10
Gene ID
112483
NCBI Accession
BC011751
OMIM
611463
Alias
SSAT-2,SSAT2,Thialysine N-epsilon-acetyltransferase,Diamine acetyltransferase 2
Background
Antibody anti-SAT2
Status
RUO
Note
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml. - 

Descripción

Spermidine/Spermine N1 Acetyltransferase 2 (SAT2) is a lesser-studied acetyltransferase enzyme that shares functional similarities with SAT1 in catalyzing the acetylation of polyamines like spermidine and spermine Although SAT2 has a lower expression profile compared to SAT1, it participates in regulating intracellular polyamine levels and influences their transport and breakdown Emerging evidence suggests SAT2 is involved in cellular responses to stress and apoptosis, particularly under conditions where polyamine metabolism is disrupted Dysregulation of SAT2 expression may contribute to cancer progression, as polyamine catabolism is critical for controlling cell proliferation, survival, and metabolic adaptation Studies also indicate that SAT2 plays a role in modulating oxidative stress and mitochondrial function, linking its activity to cellular homeostasis and stress responses While its precise physiological roles are still being defined, SAT2’s involvement in polyamine metabolism underscores its importance in maintaining cellular growth and metabolic balance

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