Sperm Surface Protein Sp17 (SPA17) Antibody
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Description
Sperm Surface Protein Sp17 (SPA17) Antibody is a Rabbit polyclonal antibody for the detection of Human Sperm Surface Protein Sp17 (SPA17).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Sperm Surface Protein Sp17 (SPA17) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q15506 |
| Gene ID | 53340 |
| NCBI Accession | NP_059121.1 |
| Background | Antibody anti-SPA17 |
| Status | RUO |
Descripción
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Sperm Surface Protein Sp17 (SPA17) Antibody
SPA17 Antibody is a Rabbit Polyclonal antibody against SPA17. This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.
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