SPA17 antibody
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Description
Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates(By similarity).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | sperm autoantigenic protein 17 (SPA17) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 25 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q15506 |
| Gene ID | 53340 |
| Alias | Sperm surface protein Sp17,Cancer/testis antigen 22 (CT22),Sp17-1,Sperm autoantigenic protein 17 (Sperm protein 17),SPA17,SP17 |
| Background | Antibody anti-SPA17 |
| Status | RUO |
| Note | Mol. Weight 25 kDa |
Descripción
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SPA17 antibody
Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates(By similarity).
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Sperm Surface Protein Sp17 (SPA17) Antibody
SPA17 Antibody is a Rabbit Polyclonal antibody against SPA17. This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.
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