SP3 / 4 Antibody

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Description
Rabbit polyclonal antibody against SP3/4 protein. Immunogen region is C-terminal.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | SP3/4 |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
Size 1 | 10 µg |
Size 2 | 100 µg |
Size 3 | 200 µg |
Size 4 | 300 µg |
Size 5 | 1 mg |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q02447, Q02446 |
Background | Antibody anti-SP3 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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SP3 / 4 Antibody
Rabbit polyclonal antibody against SP3/4 protein. Immunogen region is C-terminal.
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This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.
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