Somatostatin Receptor 4 (SSTR4) Antibody

Este producto es parte de SSTR - Somatostatin Receptor
Product Graph
260€ (50 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Somatostatin Receptor 4 (SSTR4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx241425
tested applications
ELISA, IHC

Description

SSTR4 Antibody is a Rabbit Polyclonal against SSTR4.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Somatostatin Receptor 4 (SSTR4)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
ELISA: 1/2000 - 1/5000, IHC: 1/25 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
50 µl
Size 2
100 µl
Form
Liquid
Tested Applications
ELISA, IHC
Buffer
PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P31391
Gene ID
6754
Alias
SSTR4,SRIF2B,SS-4-R,SS4-R, SS4R,SST4
Background
Antibody anti-SSTR4
Status
RUO

Descripción

SSTR4 is a G protein-coupled receptor that binds somatostatin, a peptide hormone involved in inhibiting the release of other hormones such as growth hormone, insulin, and glucagon. It primarily couples to Gi proteins, inhibiting adenylate cyclase activity and reducing cAMP levels, which results in the suppression of hormone secretion and modulation of cellular responses. SSTR4 is expressed in a variety of tissues, including the brain, pancreas, and gastrointestinal tract. In the brain, it plays a role in regulating neurotransmitter release and synaptic transmission. In the pancreas, it helps to control insulin and glucagon secretion, contributing to glucose homeostasis. Dysregulation of SSTR4 has been implicated in disorders such as acromegaly and diabetes. Somatostatin analogs that target SSTR4 are used therapeutically to control excessive hormone secretion, particularly in endocrine tumors and hormone-related disorders.

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