Sodium/Calcium Exchanger 1 (SLC8A1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Sodium/Calcium Exchanger 1 (SLC8A1) Antibody is a Rabbit polyclonal antibody for the detection of Human Sodium/Calcium Exchanger 1 (SLC8A1).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Sodium/Calcium Exchanger 1 (SLC8A1) Immunogen: Recombinant Sodium/Calcium Exchanger 1 (Ser407-Glu718) expressed in E. coli. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C for up to 2 weeks. For long-term storage, aliquot and store at -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P32418 |
| Gene ID | 6546 |
| NCBI Accession | NP_001106271.1 |
| Background | Antibody anti-SLC8A1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Related Products
Human SLC8A1 (Sodium/calcium exchanger 1) ELISA Kit
Ver Producto
SLC8A1 antibody
Ver Producto
Sodium/Calcium Exchanger 1 (SLC8A1) Antibody
In cardiac myocytes, Ca (2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca (2+) centration during contraction is primarily due to release of Ca (2+) from intracellular stores. However, some Ca (2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca (2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca (2+) that entered across the sarcolemma must be extruded from the cell. The Na (+) Ca (2+) exchanger is the primary mechanism by which the Ca (2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.
Ver Producto