Sodium Voltage-Gated Channel Beta Subunit 1 (SCN1B) Antibody
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Description
SCN1B Antibody is a Rabbit Polyclonal against SCN1B.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Sodium Voltage-Gated Channel Beta Subunit 1 (SCN1B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q07699 |
| Gene ID | 6324 |
| NCBI Accession | NP_950238.1 |
| Background | Antibody anti-SCN1B |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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Sodium Voltage-Gated Channel Beta Subunit 1 (SCN1B) Antibody
Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. SCN1B encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.
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