Sodium Iodide-Related Cotransporter (Slc5a8) Antibody

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Description
Solute Carrier Family 5 (Iodide Transporter), Member 8 Antibody is a Rabbit Polyclonal antibody against Solute Carrier Family 5 (Iodide Transporter), Member 8.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Sodium Iodide-Related Cotransporter (Slc5a8) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N695 |
| Gene ID | 160728 |
| OMIM | 608044 |
| Background | Antibody anti-Slc5a8 |
| Status | RUO |
Descripción
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Mouse Slc5a8 Antibody
Acts as an electrogenic sodium (Na (+)) and chloride (Cl-) dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na (+) :substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na (+) gradient and hence contribute to the maintenance of the energy status and function of neurons.
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Sodium Iodide-Related Cotransporter (Slc5a8) Antibody
Solute Carrier Family 5 (Iodide Transporter), Member 8 Antibody is a Rabbit Polyclonal antibody against Solute Carrier Family 5 (Iodide Transporter), Member 8.
Ver Producto