Snail Family Transcriptional Repressor 1 / SNAIL (SNAI1) Antibody
383.5€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Snail Family Transcriptional Repressor 1 / SNAIL (SNAI1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx012238
tested applications
ELISA
Description
This protein has many roles during postimplantation development. It is involved in embryonic mesoderm formation and its maintenance and may also be involved in chondrogenesis and in epithelial-mesenchymal inductive interactions.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Snail Family Transcriptional Repressor 1 / SNAIL (SNAI1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95863 |
| Gene ID | 6615 |
| OMIM | 604238 |
| Background | Antibody anti-SNAI1 |
| Status | RUO |
| Note | Concentration: Not determined. - |
Descripción
Related Products
Human SNAI1 (Snail family transcriptional repressor 1) ELISA Kit
Ver Producto
SNAI1 antibody
Involved in induction of the epithelial to mesenchymal transition(EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate(TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.
Ver Producto