SLAM Family Member 6 (SLAMF6) Antibody

312€ (50 µg)
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name
SLAM Family Member 6 (SLAMF6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx421799
tested applications
FCM
Description
SLAM Family Member 6 (SLAMF6) Antibody is a Mouse Monoclonal antibody for the detection of SLAM Family Member 6 (SLAMF6) in Human samples.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | SLAM Family Member 6 (SLAMF6)  | 
| Host | Mouse  | 
| Reactivity | Human  | 
| Clonality | Monoclonal  | 
| Conjugation | Unconjugated  | 
| Isotype | IgG1 Kappa  | 
| Clone ID | Y727  | 
| Purity | > 95% (SDS-PAGE)  | 
| Purification | Purified by Protein A/G affinity chromatography.  | 
| Size 1 | 50 µg  | 
| Size 2 | 100 µg  | 
| Form | Liquid  | 
| Tested Applications | FCM  | 
| Buffer | 0.01 M PBS, pH 7.4, 0.09% Sodium azide.  | 
| Availability | Shipped within 5-12 working days.  | 
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles.  | 
| Dry Ice | No  | 
| UniProt ID | Q96DU3  | 
| Gene ID | 114836  | 
| NCBI Accession | NP_001171643.1  | 
| Alias | Activating NK receptor,KALI,NTBA,CD352,KALIb,Ly108,NTB-A,SF2000,NK-T-B-antigen  | 
| Background | Antibody anti-SLAMF6  | 
| Status | RUO  | 
| Note | Concentration: 1 mg/ml -  | 
Descripción
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SLAM Family Member 6 (SLAMF6) Antibody
The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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