Signal Transducer CD24 (CD24) Antibody (APC)
104€ (50 tests)
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Name
Signal Transducer CD24 (CD24) Antibody (APC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx229374
Tested Applications
FCM
Description
CD24 antibody (APC) is a Rat monoclonal antibody against CD24.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Signal Transducer CD24 (CD24) |
| Host | Rat |
| Reactivity | Mouse |
| Detection Method | Laser Line: 647 Excitation/Emission: 651/660 |
| Clonality | Monoclonal |
| Conjugation | APC |
| Isotype | IgG2b Kappa |
| Size 1 | 50 tests |
| Size 2 | 25 µg |
| Size 3 | 100 tests |
| Size 4 | 100 µg |
| Size 5 | 200 tests |
| Tested Applications | FCM |
| Buffer | PBS with 0.05% Proclin300, 1% BSA. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P24807 |
| Gene ID | 12484 |
| Alias | CD24A,Signal transducer CD24,Small cell lung carcinoma cluster 4 antigen |
| Background | Antibody anti-CD24 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD24 is a small, heavily glycosylated cell surface protein that plays a crucial role in modulating immune responses, cell adhesion, and signal transduction. It is expressed in a wide range of tissues, including hematopoietic cells, neurons, epithelial cells, and cancer cells. CD24 has gained significant attention for its role in the immune system and its involvement in cancer biology. It has been implicated in both autoimmune diseases and tumor progression, making it an important molecule for understanding various pathophysiological processes. CD24 is involved in modulating immune responses, particularly in the context of inflammation, tumor immunology, and autoimmunity. It acts as a key regulator of innate immunity by interacting with various receptors, such as Siglec-10 on macrophages, to dampen inflammatory responses and promote immune tolerance. In the tumor microenvironment, CD24 can contribute to the immune evasion of cancer cells, allowing them to escape destruction by the immune system.
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