Cluster of Differentiation 24 (CD24) Antibody

Este producto es parte de CD24 - CD24 molecule
Cluster of Differentiation 24 (CD24) Antibody

Pida mas información

935106861

info@markelab.com

Precio

175€ (20 µl)

Antibody anti-CD24

proveedor

Abbexa

reference

abx001818

Tested Applications

WB, IHC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

CD24 Antibody is a Rabbit Polyclonal antibody against CD24. CD24 (known as heat stable antigen) is a small highly glycosylated GPI-linked sialoprotein. It is normally expressed at the surface of most B lymphocytes and differentiating neuroblasts, and it is also up-regulated in a wide variety of cancers. Studies have shown that CD24 functions in the regulation of B-cell apoptosis, leukocyte signal transduction, and leukocyte adhesion. Since it is highly glycosylated, the apparent molecular weight of CD24 could be variable, ranging from 30kd to 70kd. (Ref: Akihiko Sano, MD., 2009) This antibody is special to human CD24.


Background

CD24 is a small, heavily glycosylated cell surface protein that plays a crucial role in modulating immune responses, cell adhesion, and signal transduction. It is expressed in a wide range of tissues, including hematopoietic cells, neurons, epithelial cells, and cancer cells. CD24 has gained significant attention for its role in the immune system and its involvement in cancer biology. It has been implicated in both autoimmune diseases and tumor progression, making it an important molecule for understanding various pathophysiological processes. CD24 is involved in modulating immune responses, particularly in the context of inflammation, tumor immunology, and autoimmunity. It acts as a key regulator of innate immunity by interacting with various receptors, such as Siglec-10 on macrophages, to dampen inflammatory responses and promote immune tolerance. In the tumor microenvironment, CD24 can contribute to the immune evasion of cancer cells, allowing them to escape destruction by the immune system.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human, Mouse, Rat


immunogen target

Cluster of Differentiation 24 (CD24)


host

Rabbit


conjugation

Unconjugated


form

Liquid


tested applications

WB, IHC


purification

Purified by affinity chromatography.


buffer

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.


size 1

20 µl


size 2

50 µl


size 3

100 µl


size 4

200 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

CD24


dry ice

No


availability

Shipped within 5-10 working days.


alias

CD24A,Signal transducer CD24,Small cell lung carcinoma cluster 4 antigen


NCBI accession

NP_037362.1


note

This product is for research use only.


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