Signal Transducer And Activator Of Transcription 4 (STAT4) Antibody

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260€ (50 µl)

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935106861
info@markelab.com
name
Signal Transducer And Activator Of Transcription 4 (STAT4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx212146
tested applications
ELISA, IHC

Description

STAT4 Antibody is a Rabbit Polyclonal against STAT4.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Signal Transducer And Activator Of Transcription 4 (STAT4)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
ELISA: 1/1000 - 1/3000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
50 µl
Size 2
100 µl
Form
Liquid
Tested Applications
ELISA, IHC
Buffer
PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q14765
Gene ID
6775
OMIM
180300
Background
Antibody anti-STAT4
Status
RUO

Descripción

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STAT4 antibody

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

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