Signal Transducer And Activator of Transcription 4 (STAT4) Antibody

Signal Transducer And Activator of Transcription 4 (STAT4) Antibody
195€ (20 µl)

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Name
Signal Transducer And Activator of Transcription 4 (STAT4) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx002047
Tested Applications
ELISA, WB, IHC, IF/ICC

Description

STAT4 Antibody is a Rabbit Polyclonal antibody against STAT4. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Signal Transducer And Activator of Transcription 4 (STAT4)
Immunogen: Recombinant protein corresponding to STAT4. The exact sequence is proprietary.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Assay Type
Concentration: > 0.2 mg/ml
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 86 kDa  Observed MW: 93 kDa
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF/ICC
Buffer
PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q14765
Gene ID
6775
NCBI Accession
NP_003142.1
Background
Antibody anti-STAT4
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

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