Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody
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935106861
info@markelab.com
Precio
262.5€ (100 µl)
Antibody anti-SIGLEC7
proveedor
Abbexareference
abx104096Tested Applications
WB, IHC, IF/ICCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7).
Background
SIGLEC7, also known as p75/AIRM1, is an inhibitory receptor expressed on natural killer (NK) cells and some myeloid cells. It binds preferentially to α2-8-linked disialic acids found on both self and microbial surfaces, helping to suppress inappropriate immune activation. SIGLEC7 transmits inhibitory signals via immunoreceptor tyrosine-based inhibitory motifs (ITIMs), reducing NK cell-mediated cytotoxicity. This protein plays a critical role in maintaining self-tolerance and modulating responses to cancer and viral infections. It is frequently studied for its involvement in tumor immune evasion and as a target for immunotherapy.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
WB, IHC, IF/ICC
purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
size 1
100 µl
size 2
200 µl
size 3
1 ml
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
SIGLEC7
dry ice
No
availability
Shipped within 5-7 working days.
alias
p75,QA79,AIRM1,CD328,AIRM-1,CDw328,D-siglec,SIGLEC-7,SIGLECP2,SIGLEC19P,p75/AIRM1,Adhesion inhibitory receptor molecule 1
uniprot id
note
This product is for research use only.
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