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Human Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Protein
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935106861
info@markelab.com
Precio
212.5€ (10 µg)
Protein SIGLEC7
proveedor
Abbexareference
abx069071Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) is a recombinant Human protein produced in E. coli using Prokaryotic expression.
Background
SIGLEC7, also known as p75/AIRM1, is an inhibitory receptor expressed on natural killer (NK) cells and some myeloid cells. It binds preferentially to α2-8-linked disialic acids found on both self and microbial surfaces, helping to suppress inappropriate immune activation. SIGLEC7 transmits inhibitory signals via immunoreceptor tyrosine-based inhibitory motifs (ITIMs), reducing NK cell-mediated cytotoxicity. This protein plays a critical role in maintaining self-tolerance and modulating responses to cancer and viral infections. It is frequently studied for its involvement in tumor immune evasion and as a target for immunotherapy.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7)
host
E. coli
conjugation
Unconjugated
form
Lyophilized
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
SIGLEC7
dry ice
No
availability
Shipped within 5-7 working days.
alias
p75,QA79,AIRM1,CD328,AIRM-1,CDw328,D-siglec,SIGLEC-7,SIGLECP2,SIGLEC19P,p75/AIRM1,Adhesion inhibitory receptor molecule 1
uniprot id
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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