Sialic Acid Binding Ig Like Lectin 12 (SIGLEC12) Antibody
260€ (50 µl)
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Name
Sialic Acid Binding Ig Like Lectin 12 (SIGLEC12) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx211790
Tested Applications
ELISA, WB, IHC
Description
SIGLEC12 Antibody is a Rabbit Polyclonal against SIGLEC12.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Sialic Acid Binding Ig Like Lectin 12 (SIGLEC12) Immunogen: Fusion protein of human SIGLEC12. |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/1000 - 1/2000, WB: 1/200 - 1/1000, IHC: 1/25 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96PQ1 |
| Gene ID | 89858 |
| Alias | S2V,SLG,SIGLECL1,Siglec-XII,Sialic acid-binding Ig-like lectin-like 1,Siglec-12 |
| Background | Antibody anti-SIGLEC12 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
SIGLEC12 is an atypical Siglec that has lost its sialic acid-binding capacity in humans due to evolutionary mutations. It is expressed in some epithelial tissues and immune cells. Although its function remains poorly understood, SIGLEC12 has been linked to inflammation and cancer, where its altered expression might promote tumor progression.
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