Mouse Sialic Acid Binding Ig Like Lectin 12 (SIGLEC12) Protein
208€ (10 µg)
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935106861
info@markelab.com
name
Mouse Sialic Acid Binding Ig Like Lectin 12 (SIGLEC12) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069063
tested applications
WB, SDS-PAGE
Description
Recombinant Sialic Acid Binding Ig Like Lectin 12 (SIGLEC12) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Sialic Acid Binding Ig Like Lectin 12 (SIGLEC12) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 19.5 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu27-Met141 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q91Y57 |
| Alias | S2V,SLG,SIGLECL1,Siglec-XII,Sialic acid-binding Ig-like lectin-like 1,Siglec-12 |
| Background | Protein SIGLEC12 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
SIGLEC12 is an atypical Siglec that has lost its sialic acid-binding capacity in humans due to evolutionary mutations. It is expressed in some epithelial tissues and immune cells. Although its function remains poorly understood, SIGLEC12 has been linked to inflammation and cancer, where its altered expression might promote tumor progression.
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