Mouse Sialic Acid Binding Ig Like Lectin 12 (SIGLEC12) Protein

Este producto es parte de SIGLEC - sialic acid binding Ig like lectin
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208€ (10 µg)

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935106861
info@markelab.com
name
Mouse Sialic Acid Binding Ig Like Lectin 12 (SIGLEC12) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069063
tested applications
WB, SDS-PAGE

Description

Recombinant Sialic Acid Binding Ig Like Lectin 12 (SIGLEC12) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Sialic Acid Binding Ig Like Lectin 12 (SIGLEC12)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 19.5 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Leu27-Met141
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-12 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q91Y57
Alias
S2V,SLG,SIGLECL1,Siglec-XII,Sialic acid-binding Ig-like lectin-like 1,Siglec-12
Background
Protein SIGLEC12
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

SIGLEC12 is an atypical Siglec that has lost its sialic acid-binding capacity in humans due to evolutionary mutations. It is expressed in some epithelial tissues and immune cells. Although its function remains poorly understood, SIGLEC12 has been linked to inflammation and cancer, where its altered expression might promote tumor progression.

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