Sheep Leptin (LEP) Protein
273€ (20 µg)
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name
Sheep Leptin (LEP) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx263117
tested applications
SDS-PAGE
Description
Sheep Leptin Protein is a recombinant cytokine.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Leptin (LEP) |
| Origin | Sheep |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE and SEC-HPLC) |
| Size 1 | 20 µg |
| Size 2 | 100 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | Q28603 |
| Alias | OB,OBS,LEPD,Obese protein,Obesity factor |
| Background | Protein LEP |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Leptin ( LEP) is an adipokine predominantly produced by adipocytes that plays a key role in regulating energy balance, appetite, and metabolism by acting on the hypothalamus Leptin signals through its receptor (LEPR) to suppress food intake and promote energy expenditure, maintaining body weight homeostasis Circulating leptin levels are proportional to fat mass, with increased levels observed in obesity due to leptin resistance Dysregulation of leptin signaling is associated with metabolic syndrome, type 2 diabetes, and cardiovascular diseases Leptin also exerts immunomodulatory functions, influencing the activity of T cells, macrophages, and other immune cells to enhance pro-inflammatory responses It is implicated in autoimmune diseases, including rheumatoid arthritis and lupus, where elevated leptin promotes chronic inflammation Leptin’s role extends to bone metabolism, reproductive function, and wound healing, highlighting its pleiotropic effects in energy homeostasis and systemic physiology
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