Sheep Interleukin 15 (IL15) Protein

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935106861
info@markelab.com
Precio
520€ (50 µg)
Protein IL15
proveedor
Abbexareference
abx067452Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Interleukin 15 (IL15) is a recombinant Sheep protein produced in a Prokaryotic expression system (E. coli).
Background
Interleukin 15 (IL15) is a pro-inflammatory cytokine that plays a crucial role in regulating innate and adaptive immune responses, particularly by supporting the development, activation, and survival of natural killer (NK) cells and CD8+ T cells. IL-15 is essential for immune surveillance and protection against viral infections and tumors, making it an important cytokine in both immunity and immunotherapy. IL-15 was first identified as a T-cell growth factor similar to IL-2, but it is now recognized as a distinct cytokine with a unique biological role. It is expressed by a wide range of cell types, including monocytes, macrophages, dendritic cells, epithelial cells, and fibroblasts, in response to various inflammatory stimuli. Unlike many cytokines that are secreted and act in an autocrine or paracrine fashion, IL-15 primarily functions through a unique mechanism called trans-presentation, where it binds to its receptor on neighboring cells via cell-cell contact, thus delivering potent activation signals.
Características del producto
category
Proteins and Peptides
origin
Sheep
host
E. coli
immunogen target
Interleukin 15 (IL15)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
50 µg
size 2
100 µg
size 3
200 µg
size 4
500 µg
size 5
1 mg
observerd MW
Molecular Weight: Calculated MW: 14.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asn49-Ser162 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
IL15
dry ice
No
availability
Shipped within 5-12 working days.
alias
IL-15
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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