SET Domain Containing Protein 2 (SETD2) Antibody

SET Domain Containing Protein 2 (SETD2) Antibody

Pida mas información

935106861

info@markelab.com

Precio

312€ (60 µl)

Antibody anti-SETD2

proveedor

Abbexa

reference

abx002294

Tested Applications

IF/ICC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

SETD2 Antibody is a Rabbit Polyclonal antibody against SETD2. Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human, Mouse, Rat


immunogen target

SET Domain Containing Protein 2 (SETD2)


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

Liquid


tested applications

IF/ICC


purification

Purified by affinity chromatography.


recommended dilution

IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.


buffer

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.


size 1

60 µl


size 2

120 µl


size 3

200 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

SETD2


dry ice

No


availability

Shipped within 5-10 working days.


NCBI accession

NP_054878.5


note

Concentration: 1 mg/ml -


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clonality

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