SERPINE1 Antibody (Biotin)
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935106861
info@markelab.com
Precio
416€ (200 µl)
Antibody anti-SERPINE1
proveedor
Abbexareference
abx430278Tested Applications
P-ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
SERPINE1 Antibody is a Goat Polyclonal antibody against SERPINE1 (
Background
SERPINE1, also known as Plasminogen Activator Inhibitor-1 (PAI1), is a serine protease inhibitor that plays a key role in the regulation of fibrinolysis, the process that breaks down blood clots. It belongs to the serpin superfamily, which is a group of proteins involved in the inhibition of proteases. Specifically, SERPINE1 inhibits tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), both of which are enzymes responsible for converting plasminogen into plasmin, a protease that degrades fibrin, the main component of blood clots. The regulation of PAI-1 levels is crucial for maintaining the balance between clot formation and breakdown in the body. Abnormally high levels of PAI-1 are associated with thrombotic conditions, whereas deficiencies can lead to excessive bleeding.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
SERPINE1
host
Goat
isotype
IgG
conjugation
Biotin
form
Liquid
tested applications
P-ELISA, WB
purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
recommended dilution
P-ELISA: 1/64000. Optimal dilutions/concentrations should be determined by the end user.
buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
size 1
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
SERPINE1
dry ice
No
availability
Shipped within 1-3 working days.
alias
PAI,PAI1,PAI-1,PLANH1,Plasminogen activator inhibitor 1,Endothelial plasminogen activator inhibitor,Serpin E1
NCBI accession
NP_000593.1
note
Concentration: 0.5 mg/ml -
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