SERPINE1 Protein
3822€ (500 µg)
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935106861
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name
SERPINE1 Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069901
Description
SERPINE1 Protein is a recombinant Protein produced in E. coli. Plasminogen Activator Inhibitor 1. Purified Platelets and Hemostasis Antigens.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | SERPINE1 |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purification | Purified from E. coli |
| Size 1 | 500 µg |
| Form | Liquid |
| Buffer | Buffer contains no preservative. |
| Availability | Shipped within 10-20 working days. |
| Storage | Aliquot and store at -70°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | Yes |
| Alias | PAI,PAI1,PAI-1,PLANH1,Plasminogen activator inhibitor 1,Endothelial plasminogen activator inhibitor,Serpin E1 |
| Background | Protein SERPINE1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. This product is shipped with dry ice. Centrifuge before opening to ensure complete recovery of vial contents. |
Descripción
SERPINE1, also known as Plasminogen Activator Inhibitor-1 (PAI1), is a serine protease inhibitor that plays a key role in the regulation of fibrinolysis, the process that breaks down blood clots. It belongs to the serpin superfamily, which is a group of proteins involved in the inhibition of proteases. Specifically, SERPINE1 inhibits tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), both of which are enzymes responsible for converting plasminogen into plasmin, a protease that degrades fibrin, the main component of blood clots. The regulation of PAI-1 levels is crucial for maintaining the balance between clot formation and breakdown in the body. Abnormally high levels of PAI-1 are associated with thrombotic conditions, whereas deficiencies can lead to excessive bleeding.
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