Serpin B7 (SERPINB7) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Serpin B7 (SERPINB7) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx034017
tested applications
ELISA, WB, IHC, FCM
Description
SERPINB7 might function as an inhibitor of Lys-specific proteases and might influence the maturation of megakaryocytes via its action as a serpin.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Serpin B7 (SERPINB7) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75635 |
| Alias | PPKN,TP55,MEGSIN,Serpin B7 |
| Background | Antibody anti-SERPINB7 |
| Status | RUO |
| Note | Concentration: 0.4 mg/ml - |
Descripción
SERPINB7 is a member of the serpin (serine protease inhibitor) superfamily, which is a diverse group of proteins that play critical roles in regulating protease activity across various biological processes. The SERPINB7 gene is located on chromosome 18q21.3 and encodes a protein that is primarily involved in inhibiting serine proteases within the cell. This intracellular serpin is distinct in its functional roles compared to extracellular serpins that primarily function in the bloodstream or extracellular matrix. SERPINB7 has garnered attention due to its involvement in several pathological conditions, including certain skin diseases and nephrotic syndromes. Its expression is particularly noted in the kidney and skin, suggesting specialized roles in these tissues
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