Serpin B9 (SERPINB9) Antibody

Name: Serpin B9 (SERPINB9) Antibody
Brand: Abbexa
SKU: abx014874
Price: 52 EUR
Availability: OnlineOnly

Este producto es parte de SERPINB9 - serpin family B member 9

Pida mas información

935106861

info@markelab.com

Precio

52€ (10 µg)

Antibody anti-SERPINB9

proveedor

Abbexa

reference

abx014874

Tested Applications

ELISA, WB, IHC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

Rabbit polyclonal antibody against SERPINB9 protein. Immunogen region is Internal.

Background

SERPINB9, also known as Cytoplasmic Antiproteinase 9 (CAP9) or PI-9, is a member of the serpin (serine protease inhibitor) superfamily. This protein plays a critical role in protecting cells from granzyme B, a serine protease involved in inducing apoptosis in target cells. Granzyme B is a key component of the immune system's cytotoxic mechanisms, primarily used by cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells to eliminate infected or transformed cells. SERPINB9 is encoded by the SERPINB9 gene, which is located on chromosome 6p25. The protein has been highly conserved throughout evolution, underscoring its vital role in immune regulation. Unlike many other serpins that operate extracellularly, SERPINB9 is an intracellular serpin, making it an integral component of cellular defense mechanisms against protease-mediated apoptosis.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse, Rat

immunogen target

Serpin B9 (SERPINB9)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IHC

purification

Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.

recommended dilution

WB: 1/500 - 1/3000, IHC: 1/50 - 1/100, ELISA: 1/20000. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.

size 1

10 µg

size 2

100 µg

size 3

200 µg

size 4

300 µg

size 5

1 mg

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

SERPINB9

dry ice

availability

Shipped within 5-10 working days.

alias

PI9,CAP3,PI-9,CAP-3,Serpin B9,Cytoplasmic antiproteinase 3,Peptidase inhibitor 9

uniprot id

https://www.uniprot.org/uniprotkb/P50453

note

Concentration: 1 mg/ml -

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