Serpin B4 (SERPINB4) Antibody

Este producto es parte de SERPINB4 - serpin family B member 4
Product Graph
357.5€ (100 µg)

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935106861
info@markelab.com
name
Serpin B4 (SERPINB4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx122028
tested applications
ELISA, WB, IHC

Description

Rabbit Polyclonal against the SERPINB4 protein.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Serpin B4 (SERPINB4)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by antigen affinity column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB, IHC
Buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
BC017401
Alias
PI11,SCCA1,SCCA2,LEUPIN,SCCA-2,Serpin B4,Leupin,Peptidase inhibitor 11,Squamous cell carcinoma antigen 2
Background
Antibody anti-SERPINB4
Status
RUO
Note
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml. -

Descripción

SERPINB4, also known as squamous cell carcinoma antigen 2 (SCCA2), is a member of the serine protease inhibitor (SERPIN) family, specifically part of the SERPINB clade. This protein is closely related to SERPINB3, with which it shares significant sequence homology and functional similarities. Like other members of the SERPIN superfamily, SERPINB4 plays a crucial role in regulating proteolytic processes within cells, which are essential for maintaining cellular homeostasis and responding to various physiological and pathological stimuli. SERPINB4 was initially identified in the context of squamous cell carcinoma (SCC), a common form of skin cancer, where it is often overexpressed alongside SERPINB3. The gene encoding SERPINB4 is located on chromosome 18q21, within a cluster of related SERPIN genes, including SERPINB3
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