Serpin B4 (SERPINB4) Antibody (HRP)
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Description
SERPINB4 Antibody (HRP) is a Rabbit Polyclonal against SERPINB4.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Serpin B4 (SERPINB4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P48594 |
| Gene ID | 6318 |
| Alias | PI11,SCCA1,SCCA2,LEUPIN,SCCA-2,Serpin B4,Leupin,Peptidase inhibitor 11,Squamous cell carcinoma antigen 2 |
| Background | Antibody anti-SERPINB4 |
| Status | RUO |
Descripción
SERPINB4, also known as squamous cell carcinoma antigen 2 (SCCA2), is a member of the serine protease inhibitor (SERPIN) family, specifically part of the SERPINB clade. This protein is closely related to SERPINB3, with which it shares significant sequence homology and functional similarities. Like other members of the SERPIN superfamily, SERPINB4 plays a crucial role in regulating proteolytic processes within cells, which are essential for maintaining cellular homeostasis and responding to various physiological and pathological stimuli. SERPINB4 was initially identified in the context of squamous cell carcinoma (SCC), a common form of skin cancer, where it is often overexpressed alongside SERPINB3. The gene encoding SERPINB4 is located on chromosome 18q21, within a cluster of related SERPIN genes, including SERPINB3
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