Serpin A12 (SERPINA12) Antibody

Background

SERPINA12, also known as Vaspin (Visceral adipose tissue-derived serpin), is a member of the serpin (serine protease inhibitor) superfamily, which is widely recognized for its role in inhibiting serine proteases. Vaspin was first identified in 2005 in the visceral adipose tissue of Otsuka Long-Evans Tokushima Fatty (OLETF) rats, an animal model of obesity and type 2 diabetes. The discovery of Vaspin was driven by the need to understand better the molecular mechanisms linking obesity, insulin resistance, and metabolic syndrome. Since then, Vaspin has been studied extensively for its role in metabolism, inflammation, and potential therapeutic applications in treating metabolic diseases.