Serine/threonine-Protein Kinase VRK1 (VRK1) Antibody
559€ (100 µl)
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Name
Serine/threonine-Protein Kinase VRK1 (VRK1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx034922
Tested Applications
ELISA, WB
Description
Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. This antibody is supplied as crude ascites.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Serine/threonine-Protein Kinase VRK1 (VRK1) Immunogen: Purified His-tagged Human VRK1 protein |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Observed MW | Calculated MW: 45.5 kDa |
| Purification | Unpurified crude ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | Ascites containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q99986 |
| NCBI Accession | NP_003375.1 |
| Background | Antibody anti-VRK1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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