Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody (FITC)

Este producto es parte de ACVR - Activin A Receptor Type
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169€ (20 µg)

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935106861
info@markelab.com
name
Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx312736

Description

Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody (FITC) is a Rabbit Polyclonal Antibody against Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) conjugated to FITC.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Serine/threonine-Protein Kinase Receptor R3 (ACVRL1)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
FITC
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P37023
Gene ID
94
OMIM
600376
Alias
Activin receptor-like kinase 1,ALK-1,SKR3
Background
Antibody anti-ACVRL1
Status
RUO

Descripción

ACVRL1, also known as ALK1, is a type I receptor that primarily binds BMP9 and BMP10. It is critical for vascular development and endothelial cell function. ACVRL1 regulates angiogenesis through the SMAD1/5/8 signaling pathway, promoting endothelial proliferation and vessel stability. Mutations in ACVRL1 cause hereditary hemorrhagic telangiectasia (HHT), a genetic disorder characterized by abnormal blood vessel formation and recurrent bleeding. It is primarily expressed in vascular endothelial cells.

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