Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody (Biotin)
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935106861
info@markelab.com
Precio
162.5€ (20 µg)
Antibody anti-ACVRL1
proveedor
Abbexareference
abx312737Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody (Biotin) is a Rabbit Polyclonal Antibody against Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) conjugated to Biotin.
Background
ACVRL1, also known as ALK1, is a type I receptor that primarily binds BMP9 and BMP10. It is critical for vascular development and endothelial cell function. ACVRL1 regulates angiogenesis through the SMAD1/5/8 signaling pathway, promoting endothelial proliferation and vessel stability. Mutations in ACVRL1 cause hereditary hemorrhagic telangiectasia (HHT), a genetic disorder characterized by abnormal blood vessel formation and recurrent bleeding. It is primarily expressed in vascular endothelial cells.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Serine/threonine-Protein Kinase Receptor R3 (ACVRL1)
host
Rabbit
conjugation
Biotin
form
Liquid
tested applications
ELISA
purity
> 95%
purification
Purified by Protein G.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
or code
ACVRL1
dry ice
No
availability
Shipped within 5-10 working days.
alias
Activin receptor-like kinase 1,ALK-1,SKR3
uniprot id
note
This product is for research use only.
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