Serine/threonine-protein kinase receptor R3 (ACVRL1) Antibody
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935106861
info@markelab.com
Precio
287.5€ (50 µl)
Antibody anti-ACVRL1
proveedor
Abbexareference
abx349848Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
MonoclonalDescripción
Serine/threonine-protein kinase receptor R3 (ACVRL1) Antibody is a Recombinant Human Monoclonal antibody for the detection of Human ACVRL1.
Background
ACVRL1, also known as ALK1, is a type I receptor that primarily binds BMP9 and BMP10. It is critical for vascular development and endothelial cell function. ACVRL1 regulates angiogenesis through the SMAD1/5/8 signaling pathway, promoting endothelial proliferation and vessel stability. Mutations in ACVRL1 cause hereditary hemorrhagic telangiectasia (HHT), a genetic disorder characterized by abnormal blood vessel formation and recurrent bleeding. It is primarily expressed in vascular endothelial cells.
Características del producto
category
Primary Antibodies
clonality
Monoclonal
reactivity
Human
immunogen target
Serine/threonine-protein kinase receptor R3 (ACVRL1)
host
Human
conjugation
Unconjugated
form
Liquid
tested applications
ELISA
expression
Recombinant
purification
Purified by affinity chromatography.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol.
size 1
50 µl
size 2
100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ACVRL1
dry ice
No
availability
Shipped within 5-10 working days.
alias
Activin receptor-like kinase 1,ALK-1,SKR3
uniprot id
note
This product is for research use only.
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