Name: Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody
Brand: Abbexa
SKU: abx123868
Price: 175 EUR
Availability: OnlineOnly

Background

ACVRL1, also known as ALK1, is a type I receptor that primarily binds BMP9 and BMP10. It is critical for vascular development and endothelial cell function. ACVRL1 regulates angiogenesis through the SMAD1/5/8 signaling pathway, promoting endothelial proliferation and vessel stability. Mutations in ACVRL1 cause hereditary hemorrhagic telangiectasia (HHT), a genetic disorder characterized by abnormal blood vessel formation and recurrent bleeding. It is primarily expressed in vascular endothelial cells.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse, Rat

immunogen target

Serine/threonine-Protein Kinase Receptor R3 (ACVRL1)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

purification

Purified by affinity chromatography.

buffer

PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.

size 1

20 µl

size 2

50 µl

size 3

100 µl

size 4

200 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

ACVRL1

dry ice

availability

Shipped within 5-10 working days.

alias

Activin receptor-like kinase 1,ALK-1,SKR3

uniprot id

https://www.uniprot.org/uniprotkb/P37023

gene id

https://www.ncbi.nlm.nih.gov/gene/94

NCBI accession

NP_001070869.1

note

This product is for research use only.

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anti- ACVRL1 antibody

proveedor

FineTest

reference

FNab00131

Tested Applications

ELISA, WB, IHC, FC, IP

reactivity

human

status

RUO

clonality

polyclonal

Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel developme...

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