Name: Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody
Brand: Abbexa
SKU: abx312734
Price: 162.5 EUR
Availability: OnlineOnly

Background

ACVRL1, also known as ALK1, is a type I receptor that primarily binds BMP9 and BMP10. It is critical for vascular development and endothelial cell function. ACVRL1 regulates angiogenesis through the SMAD1/5/8 signaling pathway, promoting endothelial proliferation and vessel stability. Mutations in ACVRL1 cause hereditary hemorrhagic telangiectasia (HHT), a genetic disorder characterized by abnormal blood vessel formation and recurrent bleeding. It is primarily expressed in vascular endothelial cells.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Serine/threonine-Protein Kinase Receptor R3 (ACVRL1)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IF/ICC

purity

> 95%

purification

Purified by Protein G.

buffer

0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.

size 1

20 µg

size 2

50 µg

size 3

100 µg

size 4

200 µg

size 5

1 mg

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

ACVRL1

dry ice

availability

Shipped within 5-10 working days.

alias

Activin receptor-like kinase 1,ALK-1,SKR3

uniprot id

https://www.uniprot.org/uniprotkb/P37023

gene id

https://www.ncbi.nlm.nih.gov/gene/94

note

This product is for research use only.

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anti- ACVRL1 antibody

proveedor

FineTest

reference

FNab00131

Tested Applications

ELISA, WB, IHC, FC, IP

reactivity

human

status

RUO

clonality

polyclonal

Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel developme...

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