Serine/Threonine-Protein Kinase Pim-2 (PIM2) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Serine/Threonine-Protein Kinase Pim-2 (PIM2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx033773
tested applications
ELISA, WB, IHC, IP
Description
Pim proteins (Pim-1, Pim-2 and Pim-3) are oncogene-encoded serine/threonine kinases. Pim-2 is highly homologous to Pim-1 with similar oncogenic functions. Pim-2 overexpression promotes resistance to a host of apoptotic stimuli; its expression is negatively regulated by growth factor depletion. Increased levels of Pim-2 has also been observed in certain cancers.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Serine/Threonine-Protein Kinase Pim-2 (PIM2) Immunogen: KLH-conjugated synthetic peptide between 277-308 amino acids from the C-terminal region of human PIM2. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/2000, IHC-P: 1/50 - 1/100, IP: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 34.2 kDa |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9P1W9 |
| NCBI Accession | NP_006866.2 |
| Background | Antibody anti-PIM2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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Serine/Threonine-Protein Kinase Pim-2 (PIM2) Antibody
Pim proteins (Pim-1, Pim-2 and Pim-3) are oncogene-encoded serine/threonine kinases. Pim-2 is highly homologous to Pim-1 with similar oncogenic functions. Pim-2 overexpression promotes resistance to a host of apoptotic stimuli; its expression is negatively regulated by growth factor depletion. Increased levels of Pim-2 has also been observed in certain cancers.
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